Neurology covers the diseases of the brain, spinal cord, nerves, and muscles. The Department of Neurology has an extensive presence in each phase of the medical school curriculum. In Phase 1, students are introduced to the basic anatomy and function of the nervous system as well as the major diseases encountered by neurologists in Modules 6 and 7. Students can also rotate on neurology services during their clinical immersions in Phase 1. During Phase 2, students rotate through neurology as one the required core clinical clerkships. During this course, students have extensive exposure to both the inpatient and outpatient practice of neurology. In Phase 3 of the curriculum, students can select a month-long advanced clinical rotation (ACR) in either adult or pediatric neurology. They can also select shorter or more flexible electives in neurology or certain subspecialties of neurology. Various neurology-related keystone integrated science courses (KISCs) are also offered.

For more information about the Department of Neurology, please visit the department website.

Contact Info

Website:https://neuro.wustl.edu/education

Neurology Research Electives

During the fourth year, opportunities exist for many varieties of advanced clinical or research experiences.


Beau Ances, MD
Taylor Avenue Building Extension, 2nd Floor
Phone: 314-747-8423

Neuroimaging of neurodegenerative disorders. Students can work in a neuroimaging laboratory that is focused on the translational discovery of neuroimaging biomarkers for neurodegenerative diseases. The laboratory focuses on the pathogenesis of Alzheimer's disease and HIV-associated neurocognitive disorders. We are investigating the effects of neurodegenerative diseases on the brain network level using functional (blood oxygen level dependent imaging, arterial spin labeling), structural (volumetrics, diffusion tensor imaging), and metabolic (PET amyloid and tau) methods. Multiple projects that involve bioengineering, neuroimaging and infectious disease are available, depending on the interest of the student.


Randall Bateman, MD
BJCIH 9603
Phone: 314-273-9057

Diagnostic tests, biomarkers, and pathophysiology of Alzheimer’s disease and other neurologic diseases. This research elective will expose the student to translational research in the study of Alzheimer's disease and other neurodegenerative diseases. The student will participate in multiple areas of the research, including participant recruitment, consent, enrollment and the performance of clinical research studies to discover and develop diagnostic tests and biomarkers and to understand the pathophysiology of Alzheimer’s disease. Lumbar puncture for cerebrospinal fluid sample collection, blood collection and intravenous labeling methods will be demonstrated and taught. The student will participate in sample analysis, including processing for mass spectrometry quantitation, proteomic analyses, clinical analyses including determining sensitivity and specificity of tests, and application to real-world populations including diverse clinical cohorts led by the PI (SEABIRD) and the SILQ Center. Quantitation, analysis and modeling of the data will be taught in the context of data interpretation and clinical study design. The student will learn about how clinical tests and treatments are developed in medicine, advancing the leading edge of advanced medical diagnosis and treatment.


Anne H. Cross, MD
McMillan, 3rd Floor
Phone: 314-747-4591 or 314-747-0405

Understanding interactions of the immune system with the central nervous system as it relates to multiple sclerosis and other neuroimmunological disorders. Our goal is to understand how immune cells cross the blood-brain barrier and initiate the cascade of events that leads to the lesions of multiple sclerosis. We are also funded to study the effects of diet and adipokines on neuroinflammation. Depending on the time commitment of the student and their individual interests and goals, they will either assist with ongoing projects or be given a laboratory project on which to work. Projects may involve animal models of multiple sclerosis, cell culture or studies of human samples (cerebrospinal fluid, blood or autopsied specimens). Interested students should contact Dr. Cross several weeks in advance before signing up for this research to allow for sufficient planning.


Joel S. Perlmutter, MD
East Building, 2nd Floor
Phone: 314-362-6026

Pathophysiology of movement disorders. The lab is primarily interested in the etiology, pathophysiology and treatment of basal ganglia disorders. We have several studies of Parkinson disease (PD). We are testing new drugs that might rescue injured nigrostriatal neurons (a model of PD) with the potential to slow the progression of PD. For these, we use PET to measure dopamine and related pathways and to quantify motor behavior. We also have an active program developing and validating neuroimaging biomarkers for PD and for determining the integrity of the nigrostriatal pathway that includes studies in human and animal models of PD. In addition, we have an active program that combines a variety of approaches to develop biomarkers and investigate the pathophysiology of dementia associated with PD. We use PET to measure radioligand binding in PD and dystonia. We use PET to investigate drug-mediated pathways and inflammatory responses in the brain and to parse out the effects of potential therapeutic interventions. We also develop and implement MR-based methods including diffusion tensor imaging and resting-state functional connectivity to investigate the brain mechanisms underlying PD and dystonia.


Marcus E. Raichle, MD
East Building, 2nd Floor
Phone: 314-362-6907

This lab investigates in vivo brain hemodynamic, metabolic and functional studies of human cognition and emotion using cyclotron-produced isotopes and PET as well as fMRI in humans. 


Gregory Wu, MD, PhD
McMillan, 3rd Floor
Phone: 314-362-3293

Understanding how immune responses are generated that target the central nervous system. Specifically, this lab studies antigen-presenting cell contributions to autoimmune animal models of multiple sclerosis. Our goal is to understand what cellular interactions are critical to the development of immune-mediated demyelination.


NEUROL 8020 Neuro-Oncology (Clinical Elective)

The Phase III elective experience in adult neurology is designed to adapt to the individual goals and objectives of students. The elective takes place in one or two 2-week blocks that can occur among four possible venues as chosen by the student after discussion with the course director:
1. Adult Inpatient General Service
2. Adult Inpatient Stroke Service
3. Adult Inpatient Consult Service
4. Outpatient Clinics (with 8-10 clinics/week)
The combination of services and experiences will be arranged directly between the student and the Course Director prior to beginning the rotation. Students rotating on the inpatient services will work closely with neurology residents to develop neurology-specific care plans for general neurology or stroke patients and will function above a clerkship level. No call or weekend duties will be expected on this rotation. On the general consult team, students will see patients in the ER and on other services who have neurologic issues or complications. In the outpatient clinics, students will rotate between a variety of subspecialty clinics and work with a variety of attendings in order to experience the breadth of outpatient neurology.

Credit 4 units.

Typical periods offered: Medicine Year


NEUROL 8030 Neonatal Neurology (Clinical Elective)

The Neonatal Neurology elective will consist of a combination of inpatient and outpatient experiences designed to provide medical students with comprehensive exposure to the field. Through the rotation, students will actively participate in all aspects of patient care, acquiring the knowledge and skills necessary to effectively evaluate infants with a wide range of neurological disorders including encephalopathy, stroke, seizures, hypotonia, intraventricular hemorrhage, periventricular leukomalacia, and genetic disorders, among others.
   
Clinical activities will be tailored to fit the interests and goals of the individual student and include a combination of inpatient and outpatient exposures. Inpatient activities will occur in the St. Louis Children's Hospital Neonatal Intensive Unit as part of the Neonatal Neurology Consultation service. Outpatient activities will occur in the St. Louis Children's Hospital Outpatient Clinics. Students will also attend educational conferences specific to the field during the rotation, including Neonatal Neurology Clinical Conference and Neonatal Neuroradiology Conference.

Credit 2 units.

Typical periods offered: Medicine Year


NEUROL 8035 Pediatric Neurology (Clinical Elective)

The Phase III elective experience in child neurology is designed to adapt to the individual goals and objectives of students. The elective takes place among five possible venues as chosen by the student after discussion with the course director: 1. Inpatient ward service 2. FL/ED consult service 3. PICU consult service 4. Outpatient Clinics (with 8-10 clinics per week) 5. Video EEG (VEEG) monitoring service.
The combination of services and experiences will be arranged directly between the student and the Course Director prior to beginning the rotation. In outpatient clinics, students will rotate between a variety of subspecialty clinics and work with a variety of attendings in order to experience the breadth of outpatient pediatric neurology. Students rotating on the inpatient ward service will work closely with the pediatric neurology resident to develop neurology-specific care plans and will function above a clerkship level. On the FL/ED consult services, students will work with the consult attending and pediatric neurology residents on that team to see consults in the ER and other hospital floors.

Credit 4 units.

Typical periods offered: Medicine Year


NEUROL 8040 Neurointensive Care Unit (Clinical Elective)

The student will be integrated into the Critical Care Team that provides care in the Neurology/Neurosurgery ICU. Diseases frequently encountered include intracerebral hemorrhage, head trauma, subarachnoid hemorrhage, stroke, spinal cord disease, and neuromuscular disease.. The student will follow patients, participate in rounds and may participate in some procedures under supervision. Didactic sessions will be provided as conferences or lectures from the ICU attending and fellow.

Credit 4 units.

Typical periods offered: Medicine Year


NEUROL 8045 Adult Epilepsy (Clinical Elective)

Students will learn how epileptologists diagnose and manage epilepsy in adults. They will learn how to use the history and physical exam and ancillary studies such as EEG, MRI, PET, and SPECT to diagnose and manage patients with new onset epilepsy, established epilepsy, and medically intractable epilepsy. They will become familiar with the medical management of epilepsy as well as the treatment options for medically intractable epilepsy including epilepsy surgery. They will also learn how to manage the co-morbid conditions that accompany epilepsy such as depression, behavioral problems, cognitive impairment, sleep disturbance, and non-epileptic events. Students will accomplish these goals by rounding on the inpatient epilepsy service (Epilepsy Monitiring Unit and Critical Care EEG Monitoring) with the epilepsy team at Barnes-Jewish Hospital. Students will attend outpatient epilepsy clinic one half-day per week. They will attend the Adult Epilepsy Conference, EEG Review Conference, EEG/Epilepsy Didactics, and Neurology Grand Rounds.

Credit 2 units.

Typical periods offered: Medicine Year


NEUROL 8201 Neurology (Clinical Elective)

The Phase III elective experience in adult neurology is designed to adapt to the individual goals and objectives of students. The elective can occur at four possible venues chosen by the student after discussion with the course director:    1. Adult Inpatient General Service    2. Adult Inpatient Stroke Service    3. Adult Inpatient Consult Service    4. Outpatient Clinics (with 8-10 clinics per week) The combination of services and experiences will be arranged directly between the student and the Course Director prior to beginning the rotation. Students rotating on the inpatient services will work closely with neurology residents to develop neurology-specific care plans for general neurology or stroke patients and will function above a clerkship level. On the consult team, students will see patients in the ER and on other services who have neurologic issues or complications. In the outpatient clinics, students will rotate among a variety of subspecialty clinics and work with a range of attendings to experience the breadth of outpatient neurology.

Credit 4 units.

Typical periods offered: Medicine Year


NEUROL 9100 Neurology Advanced Clinical Rotation (ACR)

The Neurology Advanced Clinical Rotation (ACR) offers graduated, supervised patient care responsibility in adult or pediatric neurology, where students are expected to act and perform at the intern level. Students typically spend the rotation on one of three services:

  • Inpatient General Adult Neurology at Barnes-Jewish Hospital
  • Adult Stroke Neurology at Barnes-Jewish Hospital or
  • Inpatient General Pediatric Neurology at St. Louis Children's Hospital
(Split rotations are considered on a case-by-case basis by the ACR Director)
Under the supervision of senior residents and attending physicians, students gain increased autonomy evaluating and treating acute and chronic neurological disorders. Key responsibilities include performing complete histories and neurological examinations, independently establishing differential diagnoses and care plans, and, when possible, writing orders, admission notes, progress notes, and discharge summaries. Students manage a tailored patient load determined by case complexity and their individual clinical skills to ensure adequate experience. Additionally, ACR students are required to attend departmental rounds and clinical conferences to further advance their neurological knowledge. The student will perform a complete history and neurological examination and will independently establish a differential diagnosis and plan. When possible, they will have the opportunity to write orders and write admission notes, daily progress notes and discharge summaries. The ACR student will carry a sufficient number of patients to ensure adequate learning and experience, as determined by the complexity and number of cases on the team. The student will attend departmental rounds and clinical conferences.
   
Students will typically spend all 4 weeks on one of the above services, exceptions and modifications to the schedule will be considered on a case-by-case basis by the ACR director.
   

Credit 4 units.

Typical periods offered: Medicine Year